Establishment of induced pluripotent stem cells from schizophrenia discordant fraternal twins
oleh: Yuichiro Yada, Mika Suga, Ran Shibukawa, Yukako Sagara, Yasue Okanishi, Takako Enami, Kayoko Tsukita, Takayuki Kondo, Keiko Imamura, Genichi Sugihara, Toshiya Murai, Haruhisa Inoue
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2021-08-01 |
Deskripsi
Schizophrenia (SCZ) is one of the major psychiatric disorders. The genetic factor is certainly influential in the onset of the disease but is not decisive. There is no identified molecular/cellular marker of the disease, and the pathomechanism is still unknown. In this study, we generated human induced pluripotent stem cells (iPSCs) derived from SCZ-discordant fraternal twins, and they could contribute to elucidation of the pathomechanism of SCZ.