Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment

oleh: Michal Walczak, Ryan A. Brady, Leonardo Mancini, Claudia Contini, Roger Rubio-Sánchez, William T. Kaufhold, Pietro Cicuta, Lorenzo Di Michele

Format: Article
Diterbitkan: Nature Portfolio 2021-08-01

Deskripsi

Lipid membrane disruption is often associated with disease but is also essential to a range of biosensing and therapeutic techniques. Here, the authors report on the development of DNA-based particles that, upon exposure to an external cue, can aggregate, disrupt lipid membranes, and arrest the motion of bacteria.