Palladium-Catalyzed C(sp3)-H Arylation of Benzo[b]thiophen-3(2H)-one 1,1-Dioxide
oleh: Hailong Liu, Wenjing Li, Haiyan Fu, Hua Chen, Ruixiang Li, Yu Li
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 2019-01-01 |
Deskripsi
A new concise synthesis route of 2-phenylbenzo[b]thiophen-3(2H)-one 1,1-dioxide from benzo[b]thiophen-3(2H)-one 1,1-dioxide was developed using palladium-catalyzed C(sp3)-H arylation. Compared with the traditional route, this protocol can effectively save many steps and combine with the current research hotspot, C(sp3)-H activation. Moreover, this catalytic system is easy to operate and a good yield can be achieved.