Enzyme-responsive progelator cyclic peptides for minimally invasive delivery to the heart post-myocardial infarction
oleh: Andrea S. Carlini, Roberto Gaetani, Rebecca L. Braden, Colin Luo, Karen L. Christman, Nathan C. Gianneschi
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-04-01 |
Deskripsi
Injectable hydrogels have gained significant interest; yet, due to high viscosity, many are unsuitable for catheter delivery. Here, the authors report on cyclic peptides with low viscosity for catheter delivery, which form self-assembled peptide hydrogels following enzymatic cleavage and demonstrated delivery in vivo.