Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation

oleh: Dingfeng Li, Juan Zhang, Ming Wang, Xiaohui Li, Huarui Gong, Huiping Tang, Lin Chen, Lili Wan, Qiang Liu

Format: Article
Diterbitkan: Nature Portfolio 2018-04-01

Deskripsi

Non-coding RNAs have been shown to be key components in translational regulation. Here the authors characterize long nucleolus specific lncRNA termed LoNA, identified to play a role in protein biosynthesis by inhibiting rRNA production and ribosome biosynthesis in nucleoli.