Recrudescence of a high parasitaemia, severe Plasmodium falciparum malaria episode, treated by artesunate monotherapy

oleh: Sophie Landre, Anne-Lise Bienvenu, Patrick Miailhes, Paul Abraham, Marie Simon, Agathe Becker, Anne Conrad, Guillaume Bonnot, Yobouet Ines Kouakou, Christian Chidiac, Gilles Leboucher, Thomas Rimmelé, Laurent Argaud, Stephane Picot

Format: Article
Diterbitkan: Elsevier 2021-04-01

Deskripsi

A patient presenting with severe malaria, with hyperparasitaemia, received 7-day artesunate monotherapy. A severe recrudescence was detected and attributed to hyperparasitaemia, monotherapy and a polyclonal infection without Kelch 13 gene mutation. A second treatment with artesunate, then quinine, followed by artemether-lumefantrine, was successful.