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One-pot aminobenzylation of aldehydes with toluenes
oleh: Zhiting Wang, Zhipeng Zheng, Xinyu Xu, Jianyou Mao, Patrick J. Walsh
Format: | Article |
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Diterbitkan: | Nature Portfolio 2018-08-01 |
Deskripsi
Amines are common targets in synthetic chemistry as they often display biological activity. Here, the authors report a one-pot aminobenzylation of aldehydes with readily available toluenes in presence of a sodium amide derivative and a cesium salt additive generating an array of valuable 1,2-diarylethylamine compounds.