Nkx2-5 defines distinct scaffold and recruitment phases during formation of the murine cardiac Purkinje fiber network

oleh: Caroline Choquet, Robert G. Kelly, Lucile Miquerol

Format: Article
Diterbitkan: Nature Portfolio 2020-10-01

Deskripsi

Here, the authors apply genetic fate mapping and temporal clonal analysis to study progenitor recruitment and network morphogenesis of murine cardiac Purkinje fibers. Additionally, they characterize how transcription factor dosage regulates cell fate divergence during distinct phases of this process.