New Eudesmane-Type Sesquiterpenoids from the Mangrove-Derived Endophytic Fungus Penicillium sp. J-54
oleh: Liuming Qiu, Pei Wang, Ge Liao, Yanbo Zeng, Caihong Cai, Fandong Kong, Zhikai Guo, Peter Proksch, Haofu Dai, Wenli Mei
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2018-03-01 |
Deskripsi
Four new eudesmane-type sesquiterpenoids, penicieudesmol A–D (1–4), were isolated from the fermentation broth of the mangrove-derived endophytic fungus Penicillium sp. J-54. Their structures were determined by spectroscopic methods, the in situ dimolybdenum CD method, and modified Mosher’s method. The bioassays results showed that 2 exhibited weak cytotoxicity against K-562 cells.