An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways

oleh: Ryan D. Pardy, Stefanie F. Valbon, Brendan Cordeiro, Connie M. Krawczyk, Martin J. Richer

Format: Article
Diterbitkan: Nature Portfolio 2021-06-01

Deskripsi

The CD8 T cell response to Zika virus is known to be a critical component of the host immune response to infection. Here the authors show a Zika virus isolate specific disruption of antigen processing that impacts the host response and impairs viral clearance providing evidence of isolate specific impacts on the immune response to infection