WNT: an unexpected tumor suppressor in medulloblastoma
oleh: Branavan Manoranjan, Ashley A. Adile, Chitra Venugopal, Sheila K. Singh
| Format: | Article |
|---|---|
| Diterbitkan: | Taylor & Francis Group 2020-11-01 |
Deskripsi
Medulloblastoma (MB) represents the most common malignant pediatric brain tumor and is defined by four molecular subgroups with WNT MB having the most favorable prognosis. Our work provides a rational therapeutic option in which the protective effects of WNT-driven MBs may be augmented in Group 3 and 4 MB.