The force required to remove tubulin from the microtubule lattice by pulling on its α-tubulin C-terminal tail

oleh: Yin-Wei Kuo, Mohammed Mahamdeh, Yazgan Tuna, Jonathon Howard

Format: Article
Diterbitkan: Nature Portfolio 2022-06-01

Deskripsi

Tubulin, the building blocks of microtubules, can be removed from the microtubule wall by mechanical forces. Using single-molecule methods, the authors show that tubulin partially unfolds prior to its removal and determined the tubulin-extraction force.