Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium

oleh: Sanja Vickovic, Denis Schapiro, Konstantin Carlberg, Britta Lötstedt, Ludvig Larsson, Franziska Hildebrandt, Marina Korotkova, Aase H. Hensvold, Anca I. Catrina, Peter K. Sorger, Vivianne Malmström, Aviv Regev, Patrik L. Ståhl

Format: Article
Diterbitkan: Nature Portfolio 2022-02-01

Deskripsi

Sanja Vickovic et al. use spatial transcriptomics to probe the local synovial tissue interactions in rheumatoid arthritis (RA) patients. Their results provide a valuable resource to understand the spatial organisation of cell populations in the synovium in the context of RA-associated inflammation.