Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells
oleh: Timo A. Lehti, Maria I. Pajunen, Maria S. Skog, Jukka Finne
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-12-01 |
Deskripsi
Eukaryotic organisms are continuously exposed to bacteriophages, but these are not thought to enter non-phagocytic cells. Here, Lehti et al. show that a bacteriophage can bind to a specific receptor on the surface of human neuroblastoma cells in vitro, and be internalized via the endolysosomal route.