Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments
oleh: Damian Dudka, Anna Noatynska, Chris A. Smith, Nicolas Liaudet, Andrew D. McAinsh, Patrick Meraldi
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-05-01 |
Deskripsi
Single microtubules (MTs) can move chromosomes, but it is unclear why kinetochores bind up to 20 MTs. Here, the authors decrease the number of kinetochore MTs with BAL27862 and see lagging chromosomes, suggesting that numerous kinetochore MTs provide force ensuring robust chromosomal segregation.