Coordination Compounds of Nickel(II) with 3,5–Dibromo–Salicylaldehyde: Structure and Interaction with Biomolecules
oleh: Georgios I. Psarras, Ariadni Zianna, Antonios G. Hatzidimitriou, George Psomas
| Format: | Article |
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| Diterbitkan: | MDPI AG 2024-05-01 |
Deskripsi
Three neutral nickel(II) complexes of 3,5–dibromo–salicylaldehyde (3,5–diBr–saloH) were synthesized in the presence or absence of 1,10–phenanthroline (phen) or its derivative 2,9–dimethyl–1,10–phenanthroline (neoc) as co–ligands, namely [Ni(3,5–diBr–salo)<sub>2</sub>(neoc)] (complex <b>1</b>), [Ni(3,5–diBr–salo)<sub>2</sub>(phen)] (complex <b>2</b>) and [Ni(3,5–diBr–salo)<sub>2</sub>(H<sub>2</sub>O)<sub>2</sub>] (complex <b>3</b>), and were characterized by various techniques. The crystal structure of [Ni(3,5–diBr–salo)<sub>2</sub>(neoc)] was determined by single-crystal X-ray crystallography. According to employed studying techniques, the complexes interact tightly with calf-thymus DNA by an intercalative fashion. Furthermore, compounds <b>1–3</b> bind tightly and reversibly to human and bovine serum albumin.