The cryo-EM structure of the SNX–BAR Mvp1 tetramer
oleh: Dapeng Sun, Natalia V. Varlakhanova, Bryan A. Tornabene, Rajesh Ramachandran, Peijun Zhang, Marijn G. J. Ford
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-03-01 |
Deskripsi
SNX-BAR proteins are a family of PX and BAR domain-containing proteins with pivotal roles in trafficking processes. Here authors present the cryo-EM structure of the full-length fungal SNX-BAR Mvp1, which is an autoinhibited tetramer and provides critical insight into SNX-BAR function and regulation.