Genomic architecture and prediction of censored time-to-event phenotypes with a Bayesian genome-wide analysis
oleh: Sven E. Ojavee, Athanasios Kousathanas, Daniel Trejo Banos, Etienne J. Orliac, Marion Patxot, Kristi Läll, Reedik Mägi, Krista Fischer, Zoltan Kutalik, Matthew R. Robinson
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-04-01 |
Deskripsi
Few genome-wide association studies have explored the genetic architecture of age-of-onset for traits and diseases. Here, the authors develop a Bayesian approach to improve prediction in timing-related phenotypes and perform age-of-onset analyses across complex traits in the UK Biobank.