Site-selective electrooxidation of methylarenes to aromatic acetals

oleh: Peng Xiong, Huai-Bo Zhao, Xue-Ting Fan, Liang-Hua Jie, Hao Long, Pin Xu, Zhan-Jiang Liu, Zheng-Jian Wu, Jun Cheng, Hai-Chao Xu

Format: Article
Diterbitkan: Nature Portfolio 2020-06-01

Deskripsi

Benzylic oxygenation of methylarenes is a direct but challenging method for aldehyde synthesis from simple starting materials. Here, the authors show an electrochemical, site-selective method for the oxidation of methyl benzoheterocycles to aromatic acetals without using chemical oxidants or transition metal catalysts.