Structural insights into the peptide selectivity and activation of human neuromedin U receptors

oleh: Chongzhao You, Yumu Zhang, Peiyu Xu, Sijie Huang, Wanchao Yin, H. Eric Xu, Yi Jiang

Format: Article
Diterbitkan: Nature Portfolio 2022-04-01

Deskripsi

Neuromedin U receptors (NMURs) are potential drug targets for obesity and inflammatory disorders. Here, the authors report structural basis for neuromedin recognition and activation mechanism of NMURs.