A Low-Producing Haplotype of Interleukin-6 Disrupting CTCF Binding Is Protective against Severe COVID-19
oleh: Tao Chen, Yu-Xin Lin, Yan Zha, Ying Sun, Jinxiu Tian, Zhiying Yang, Shan-Wen Lin, Fuxun Yu, Zi-Sheng Chen, Bo-Hua Kuang, Jin-Ju Lei, Ying-jie Nie, Yonghao Xu, Dong-Bo Tian, Ying-Zi Li, Bin Yang, Qiang Xu, Li Yang, Nanshan Zhong, Meizhen Zheng, Yimin Li, Jincun Zhao, Xiang-Yan Zhang, Lin Feng
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-10-01 |
Deskripsi
Overproduction of cytokine interleukin-6 (IL-6) is a hallmark of severe COVID-19 and is believed to play a critical role in exacerbating the excessive inflammatory response. Polymorphisms in IL-6