Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development

oleh: Marcin J. Szafran, Tomasz Małecki, Agnieszka Strzałka, Katarzyna Pawlikiewicz, Julia Duława, Anna Zarek, Agnieszka Kois-Ostrowska, Kim C. Findlay, Tung B. K. Le, Dagmara Jakimowicz

Format: Article
Diterbitkan: Nature Portfolio 2021-09-01

Deskripsi

Streptomyces bacteria have a linear chromosome and a complex life cycle, including development of multi-genomic hyphae that differentiate into mono-genomic exospores. Here, Szafran et al. show that the chromosome of Streptomyces venezuelae undergoes substantial remodelling during sporulation, from an ‘open’ to a ‘closed’ conformation.