Posttranslational Regulation of Botulinum Neurotoxin Production in Clostridium botulinum Hall A- <i>hyper</i>
oleh: Heather N’te Inzalaco, William H. Tepp, Chase Fredrick, Marite Bradshaw, Eric A. Johnson, Sabine Pellett
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-08-01 |
Deskripsi
Botulinum neurotoxin (BoNT) is a public health and bioterrorism concern as well as an important and widely used pharmaceutical, yet the regulation of its synthesis by BoNT-producing clostridia is not well understood. This paper highlights the role of environmentally controlled posttranslational regulatory mechanisms influencing processing and stability of biologically active BoNTs produced by C. botulinum