Immune system dysregulation preceding a case of laboratory-confirmed zoster/dermatitis on board the International Space Station

oleh: Satish K. Mehta, PhD, Rahul Suresh, MD, Keith Brandt, MD, Douglass M. Diak, PhD, Scott M. Smith, PhD, Sara R. Zwart, PhD, Grace Douglas, PhD, Mayra Nelman-Gonzalez, BA, Simon Clemett, PhD, Tyson Brunstetter, OD, PhD, Brian E. Crucian, PhD

Format: Article
Diterbitkan: Elsevier 2024-05-01

Deskripsi

A case report detailing, for the first time, a case of laboratory-confirmed zoster in an astronaut on board the International Space Station is presented. The findings of reduced T-cell function, cytokine imbalance, and increased stress hormones which preceded the event are detailed. Relevance for deep space countermeasures is discussed.