NmcA Carbapenem-hydrolyzing Enzyme in Enterobacter cloacae in North America
oleh: Sudha Pottumarthy, Ellen Smith Moland, Stefan Juretschko, Susan R. Swanzy, Kenneth S. Thomson, Thomas R. Fritsche
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2003-08-01 |
Deskripsi
An imipenem-resistant Enterobacter cloacae isolate was recovered from the blood of a patient with a hematologic malignancy. Analytical isoelectric focusing, inhibitor studies, hydrolysis, induction assays, and molecular sequencing methods confirmed the presence of a NmcA carbapenem-hydrolyzing enzyme. This first report of NmcA detected in North America warrants further investigation into its distribution and clinical impact.