Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life
oleh: Melanie R. Neeland, Sandra Andorf, Monali Manohar, Diane Dunham, Shu-Chen Lyu, Thanh D. Dang, Rachel L. Peters, Kirsten P. Perrett, Mimi L. K. Tang, Richard Saffery, Jennifer J. Koplin, Kari C. Nadeau
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-02-01 |
Deskripsi
Food allergy is triggered by IgE, but some individuals are not allergic to peanuts despite making peanut-specific IgE, and are considered peanut-tolerant. Here, the authors identify differences in blood immune cell composition of peanut-allergic and tolerant infants using mass cytometry, which may help uncover the mechanism of allergic tolerance.