Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy
oleh: Jose Angel Regla-Nava, Annie Elong Ngono, Karla M. Viramontes, Anh-Thy Huynh, Ying-Ting Wang, Anh-Viet T. Nguyen, Rebecca Salgado, Anila Mamidi, Kenneth Kim, Michael S. Diamond, Sujan Shresta
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-08-01 |
Deskripsi
Heterologous immunity can confer protection between related viruses. Here the authors show that prior exposure to Dengue virus can protect against subsequent infection with Zika virus in the context of pregnancy, and crucially can prevent demise of the fetus in murine models of infection.