Synthesis of pyrazolopyrimidinones using a “one-pot” approach under microwave irradiation
oleh: Mark Kelada, John M. D. Walsh, Robert W. Devine, Patrick McArdle, John C. Stephens
| Format: | Article |
|---|---|
| Diterbitkan: | Beilstein-Institut 2018-05-01 |
Deskripsi
A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established. A variety of substituents was tolerated at the 2 and 5 positions, including functionalized aryls, heterocycles, and alkyl groups.