Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance
oleh: Hua Mao, Luge Li, Qiying Fan, Aude Angelini, Pradip K. Saha, Huaizhu Wu, Christie M. Ballantyne, Sean M. Hartig, Liang Xie, Xinchun Pi
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-03-01 |
Deskripsi
Type 2 diabetes is associated with chronic inflammation and is characterized by insulin resistance. Here, the authors identify a crucial role for endothelial BMPER function in glucose homeostasis, and BMPER overexpression was shown to alleviate insulin resistance and hyperglycemia in diabetic mice.