Dynamic reorganization of the actin cytoskeleton [version 1; referees: 2 approved]

oleh: Gaëlle Letort, Hajer Ennomani, Laurène Gressin, Manuel Théry, Laurent Blanchoin

Format: Article
Diterbitkan: F1000 Research Ltd 2015-10-01

Deskripsi

Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of actin-based structures. Although the biochemical composition and filament organization of these structures are different, they often emerge from a common origin. This is possible because the actin structures are highly dynamic. Indeed, they assemble, grow, and disassemble in a time scale of a second to a minute. Therefore, the reorganization of a given actin structure can promote the formation of another. Here, we discuss such transitions and illustrate them with computer simulations.