Mechanical forces drive ordered patterning of hair cells in the mammalian inner ear
oleh: Roie Cohen, Liat Amir-Zilberstein, Micha Hersch, Shiran Woland, Olga Loza, Shahar Taiber, Fumio Matsuzaki, Sven Bergmann, Karen B. Avraham, David Sprinzak
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-10-01 |
Deskripsi
The periodic organization of cells is typically associated with mechanisms based on intercellular signaling such as lateral inhibition and Turing patterning. Here the authors show that hair cells in the inner ear rearrange gradually into a checkerboard-like pattern through a tissue-wide shear motion that coordinates intercalation and delamination events.