Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Multiscale biomedical imaging at the SYRMEP beamline of Elettra - Closing the gap between preclinical research and patient applications
oleh: Christian Dullin, Francesca di Lillo, Angelika Svetlove, Jonas Albers, Willi Wagner, Andrea Markus, Nicola Sodini, Diego Dreossi, Frauke Alves, Giuliana Tromba
Format: | Article |
---|---|
Diterbitkan: | Elsevier 2021-02-01 |
Deskripsi
Here we present the specifications and capabilities of the SYRMEP (SYnchrotron Radiation for MEdical Physics) beamline of the Italian Synchrotron “Elettra” in Trieste. SYRMEP was designed to provide X-ray imaging in an energy range that fits both biomedical research and clinical applications on patients. Additionally, SYRMEP covers a spatial resolution range of 100 μm down to 1 μm (1/50th the width of a human hair) with a comparably wide field-of-view (FOV), which enables studies in large specimens and therefore closes the gap between micro computed tomography (CT) in biomedical research and clinical CT imaging. Moreover, the possible long sample-to-detector distance allows for an effective use of free-propagation phase contrast that increases dose efficacy and soft-tissue contrast. These parameters and their function are further discussed on a set of examples of biomedical applications.