Interactions between comorbidity and treatment of chronic lymphocytic leukemia: results of German Chronic Lymphocytic Leukemia Study Group trials
oleh: Valentin Goede, Paula Cramer, Raymonde Busch, Manuela Bergmann, Martina Stauch, Georg Hopfinger, Stephan Stilgenbauer, Hartmut Döhner, Anne Westermann, Clemens M. Wendtner, Barbara Eichhorst, Michael Hallek
| Format: | Article |
|---|---|
| Diterbitkan: | Ferrata Storti Foundation 2014-06-01 |
Deskripsi
This study investigated the impact of comorbidity in 555 patients with chronic lymphocytic leukemia enrolled in two trials of the German Chronic Lymphocytic Leukemia Study Group on first-line treatment with fludarabine plus cyclophosphamide, fludarabine, or chlorambucil. Patients with two or more comorbidities and patients with less than two comorbidities differed in overall survival (71.7 versus 90.2 months; P