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OBJETIVE: To evaluate a sample of patients with persistent facial pain unresponsive to prior treatments. METHODS: Hospital records of 26 patients with persistent facial pain were reviewed (20 female and 6 male). RESULTS: Patients were classified into three groups according to their presenting symptoms: a)Group I, eight patients (30.7%) with severe, diffuse pain at the face, teeth or head; b)Group II, eight patients (30.7%) with chronic non-myofascial pain and; c)Group III, ten patients with chronic myofascial pain (38.4%). We find 11 different diagnoses among the 26 patients: pulpitis(7), leukemia(1), oropharyngeal tumor(1), atypical odontalgia(1), Eagle's syndrome(1), trigeminal neuralgia(4), continuous neuralgia(1), temporomandibular disorders (9), fibromyalgia (2), tension-type headache(1), conversion hysteria(2). After the treatment program all patients had a six-month follow-up period with pain relief, except the patient with tumor. CONCLUSION: The wide variability of orofacial pain diagnosis (benign to life-threatening diseases) indicates the necessity to reevaluate patients presenting recurrent pain that is refractory to the usual treatments.<br>OBJETIVO: Avaliar uma amostra de doentes com dor facial persistente. MÉTODO: Foram revisados 26 prontuários de doentes com dor facial persistente (20 mulheres e 6 homens). RESULTADOS: Classificação dos doentes, após o diagnóstico: a)Grupo I, oito pacientes (30,7%) com dor facial difusa de fortíssima intensidade; b)Grupo II, oito pacientes (30,7%) com dor crônica de natureza não-miofascial e; c)Grupo III, dez pacientes com dor crônica miofascial (38,4%). Foram encontrados 11 diagnósticos diferentes entre os 26 pacientes: pulpites(7), leucemia(1), tumor de orofaringe(1), odontalgia atípica(1), síndrome de Eagle(1), neuralgia idiopática do trigêmeo(4), neuralgia atípica(1), disordens temporomandibular (9), fibromialgia(2) cefaléia tipo-tensão(1), histeria de conversão(2). O acompanhamento dos doentes, após receberem a respectiva terapia, foi de seis meses, com alívio da dor, exceto para o doente com tumor de orofaringe. CONCLUSÃO: A variabilidade das fontes da dor facial inclui doenças benignas e doenças graves, sendo indispensável a reavaliaçâo de doentes que não respondem aos tratamentos convencionais para a dor.