Tau deposition is associated with functional isolation of the hippocampus in aging
oleh: Theresa M. Harrison, Anne Maass, Jenna N. Adams, Richard Du, Suzanne L. Baker, William J. Jagust
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-10-01 |
Deskripsi
Deposition of tau protein aggregates occurs during aging and Alzheimer disease. Here, the authors show that tau burden in the anterior-temporal memory network is associated with disrupted fMRI connectivity and functional isolation of the hippocampus from other memory network components.