Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons

oleh: Zhibing Tan, Yu Liu, Wang Xi, Hui-fang Lou, Liya Zhu, Zhifei Guo, Lin Mei, Shumin Duan

Format: Article
Diterbitkan: Nature Portfolio 2017-01-01

Deskripsi

Astrocyte in the brain regulates synaptic transmission by releasing gliotransmitters. Here, Tan and colleagues use optogenetic stimulation of astrocytes to show differential neuronal subtype-specific purinoceptor responses to astrocytic ATP release to affect network excitability.