SARS-CoV-2 escape from cytotoxic T cells during long-term COVID-19
oleh: Oksana V. Stanevich, Evgeniia I. Alekseeva, Maria Sergeeva, Artem V. Fadeev, Kseniya S. Komissarova, Anna A. Ivanova, Tamara S. Simakova, Kirill A. Vasilyev, Anna-Polina Shurygina, Marina A. Stukova, Ksenia R. Safina, Elena R. Nabieva, Sofya K. Garushyants, Galya V. Klink, Evgeny A. Bakin, Jullia V. Zabutova, Anastasia N. Kholodnaia, Olga V. Lukina, Irina A. Skorokhod, Viktoria V. Ryabchikova, Nadezhda V. Medvedeva, Dmitry A. Lioznov, Daria M. Danilenko, Dmitriy M. Chudakov, Andrey B. Komissarov, Georgii A. Bazykin
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
Here, the authors report accelerated intrahost evolution of SARS-CoV-2 in an immunocompromised patient with non-Hodgkin’s lymphoma with 318 days long COVID-19, and show that changes in the viral genome resulted in escape from T cellular immune response.