NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors
oleh: Shivanand Pudakalakatti, Alessandra Audia, Anirudh Mukhopadhyay, José S. Enriquez, Dontrey Bourgeois, Nabihah Tayob, Niki M. Zacharias, Steven W. Millward, Daniel Carson, Mary C. Farach-Carson, Frederick F. Lang, Amy B. Heimberger, Krishna P. Bhat, Pratip K. Bhattacharya
| Format: | Article |
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| Diterbitkan: | MDPI AG 2021-10-01 |
Deskripsi
“Tumor-educated platelets” have recently generated substantial interest for the diagnosis of cancer. We hypothesized that tumor educated platelets from patients with brain tumors will reflect altered metabolism compared to platelets from healthy volunteers. Here, in a pilot study, we have employed nuclear magnetic resonance (NMR) spectroscopy in platelets from brain tumor patients to demonstrate altered metabolism compared to the platelets obtained from healthy volunteers.