TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses

oleh: Tatjana Lalic, Aiste Steponenaite, Liting Wei, Sridhar R. Vasudevan, Alistair Mathie, Stuart N. Peirson, Gurprit S. Lall, M. Zameel Cader

Format: Article
Diterbitkan: Nature Portfolio 2020-09-01

Deskripsi

The suprachiasmatic nucleus (SCN) ensures rhythmic electrical activity that varies between day and night to determine circadian behaviours. The authors show that TRESK channels provide a feedback mechanism to maintain the SCN in the appropriate state for nocturnal light-induced behavioural changes.