Super-wide-field two-photon imaging with a micro-optical device moving in post-objective space

oleh: Shin-Ichiro Terada, Kenta Kobayashi, Masamichi Ohkura, Junichi Nakai, Masanori Matsuzaki

Format: Article
Diterbitkan: Nature Portfolio 2018-09-01

Deskripsi

Recording the activity of neurons over large brain regions requires expanding the field of view of the optics without losing on spatial and temporal resolution. Here, the authors report a micro-opto-mechanical device that enables two-photon imaging across distant motor areas around 6 mm apart in the mouse.