Differential lateral and basal tension drive folding of Drosophila wing discs through two distinct mechanisms

oleh: Liyuan Sui, Silvanus Alt, Martin Weigert, Natalie Dye, Suzanne Eaton, Florian Jug, Eugene W. Myers, Frank Jülicher, Guillaume Salbreux, Christian Dahmann

Format: Article
Diterbitkan: Nature Portfolio 2018-11-01

Deskripsi

Epithelial folding has mainly been linked to forces acting in the apical actomyosin network of cells. Here, the authors show using live imaging that two distinct mechanisms, changes in basal surface tension and changes in lateral surface tension, drive the formation of two folds in the Drosophila wing disc.