CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns
oleh: Simon D. van Haren, Gabriel K. Pedersen, Azad Kumar, Tracy J. Ruckwardt, Syed Moin, Ian N. Moore, Mahnaz Minai, Mark Liu, Jensen Pak, Francesco Borriello, Simon Doss-Gollin, Elisabeth M. S. Beijnen, Saima Ahmed, Michaela Helmel, Peter Andersen, Barney S. Graham, Hanno Steen, Dennis Christensen, Ofer Levy
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2022-08-01 |
Deskripsi
Respiratory syncytial virus is a major pathogen with burden observed and associated with childhood infection. Here the authors characterise a cationic adjuvant formulation and show single immunisation results in protection in a murine neonate model of respiratory syncytial virus infection.