Molecular characterization of breast cancer CTCs associated with brain metastasis
oleh: Debasish Boral, Monika Vishnoi, Haowen N. Liu, Wei Yin, Marc L. Sprouse, Antonio Scamardo, David S. Hong, Tuan Z. Tan, Jean P. Thiery, Jenny C. Chang, Dario Marchetti
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-08-01 |
Deskripsi
Characterization of CTCs derived from breast cancer patients with brain metastasis (BCBM) may allow for early diagnosis of brain metastasis and/or help for treatment choice and its efficacy. In this study, the authors identify a unique signature, based on patient-derived CTCs transcriptomes, for BCBM- CTCs that is different from primary tumors.