Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide
oleh: Richard J. Ingham, Claudio Battilocchio, Joel M. Hawkins, Steven V. Ley
| Format: | Article |
|---|---|
| Diterbitkan: | Beilstein-Institut 2014-03-01 |
Deskripsi
Here we describe the use of a new open-source software package and a Raspberry Pi® computer for the simultaneous control of multiple flow chemistry devices and its application to a machine-assisted, multi-step flow preparation of pyrazine-2-carboxamide – a component of Rifater®, used in the treatment of tuberculosis – and its reduced derivative piperazine-2-carboxamide.