Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides

oleh: Chi Wai Cheung, Xile Hu

Format: Article
Diterbitkan: Nature Portfolio 2016-08-01

Deskripsi

Direct synthesis of aryl amines from nitroarenes avoids the waste and potential functional group incompatibility of first reducing to anilines. Here, the authors report an iron catalysed reductive coupling of nitroarenes with alkyl halides to form a wide range of (hetero)aromatic amines.