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Case report: A rare case of malignant solitary fibrous tumor in an adult with an epithelioid pattern in the occipital region
oleh: Ke Huang, Wen-wen Liu, Xiu-wen Chen, Yin-hua Hao, Sen-yuan Luo, Ling-ling Yuan, Yu-gang Huang, Xian-bin Tang
Format: | Article |
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Diterbitkan: | Frontiers Media S.A. 2024-08-01 |
Deskripsi
We illustrated a rare case of malignant solitary fibrous tumor (MSFT) with epithelioid morphology in the occipital region of a 59-year-old female, in which a rare NAB2ex7-STAT6 exon15/16 double fusion subtype was detected by the Next-generation sequencing (NGS) and STAT6 immunohistochemistry (IHC) was diffusely and strongly positively expressed, without recurrence after 20 months of postoperative follow-up. The morphological and molecular genetic aspects and the differential diagnosis are described, and the relevant literature was assessed in order to broaden our understanding and diagnostic capability of this malignancy.