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Reconstructing 3D deformation dynamics for curved epithelial sheet morphogenesis from positional data of sparsely-labeled cells
oleh: Yoshihiro Morishita, Ken-ichi Hironaka, Sang-Woo Lee, Takashi Jin, Daisuke Ohtsuka
Format: | Article |
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Diterbitkan: | Nature Portfolio 2017-05-01 |
Deskripsi
Quantifying deformation patterns of curved epithelial sheets is challenging owing to imaging difficulties. Here the authors develop a method to obtain a quantitative description of 3D tissue deformation dynamics from a small set of cell positional data and applied it to chick forebrain morphogenesis.