Reconstructing 3D deformation dynamics for curved epithelial sheet morphogenesis from positional data of sparsely-labeled cells

oleh: Yoshihiro Morishita, Ken-ichi Hironaka, Sang-Woo Lee, Takashi Jin, Daisuke Ohtsuka

Format: Article
Diterbitkan: Nature Portfolio 2017-05-01

Deskripsi

Quantifying deformation patterns of curved epithelial sheets is challenging owing to imaging difficulties. Here the authors develop a method to obtain a quantitative description of 3D tissue deformation dynamics from a small set of cell positional data and applied it to chick forebrain morphogenesis.