Noninvasive Test for Tuberculosis Detection among Primates
oleh: Tiffany M. Wolf, Lawrence Mugisha, Fernanda Miyagaki Shoyama, Melanie J. O’Malley, JoAnne L. Flynn, Benon Asiimwe, Dominic A. Travis, Randall S. Singer, Srinand Sreevatsan
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2015-03-01 |
Deskripsi
Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.