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Immune checkpoint inhibitor‐related haemophagocytic lymphohistiocytosis in a patient with non‐small cell lung carcinoma
oleh: Setsuko Oyama, Tatsuya Shirai, Yukiko Abe, Maya Tsuchiya, Toshiya Inui, Kozo Suhara, Satoshi Noto, Mitsuhiro Kamimura
Format: | Article |
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Diterbitkan: | Wiley 2023-04-01 |
Deskripsi
Key message Hemophagocytic lymphohistiocytosis (HLH) has been reported as a rare complication of immune checkpoint inhibitors (ICI); however, ICI‐related HLH is a life‐threatening and comparatively late adverse event. Early diagnosis is critical, and it should be included in the differential diagnosis especially in patients with cytopenia with fever and hyperferritinaemia.