Quorum sensing modulates the formation of virulent Legionella persisters within infected cells
oleh: Nicolas Personnic, Bianca Striednig, Emmanuelle Lezan, Christian Manske, Amanda Welin, Alexander Schmidt, Hubert Hilbi
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-11-01 |
Deskripsi
The pathogenic bacterium Legionella pneumophila infects lung macrophages and environmental amoebae. Here, Personnic et al. show that the pathogen reversibly forms virulent, antibiotic-tolerant subpopulations during infection of macrophages and amoebae, in a process regulated by the Lqs quorum-sensing system.